Tropomyosin 1 genetically constrains in vitro hematopoiesis
نویسندگان
چکیده
منابع مشابه
Hematopoiesis In Vitro Coexists
The role of natural killer (NK) lymphocytes in the regulation of human hematopoiesis is controversial. NK-mediated inhibition of colony formation of hematopoietic progenitor cells has been irregularly reported for various cell lineages. In an effort to clarify such disparate findings. we studied the interaction of clearly defined NK and partially purified progenitor cell populations. Cell sorte...
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Actin filaments assemble into a variety of networks to provide force for diverse cellular processes [1]. Tropomyosins are coiled-coil dimers that form head-to-tail polymers along actin filaments and regulate interactions of other proteins, including actin-depolymerizing factor (ADF)/cofilins and myosins, with actin [2-5]. In mammals, >40 tropomyosin isoforms can be generated through alternative...
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ژورنال
عنوان ژورنال: BMC Biology
سال: 2020
ISSN: 1741-7007
DOI: 10.1186/s12915-020-00783-7